학술논문
Effects of Prone Positioning on Lung Protection in Patients with Acute Respiratory Distress Syndrome
Document Type
Academic Journal
Author
Source
American Journal of Respiratory and Critical Care Medicine. Aug 15, 2013 188(4):440-448
Subject
Language
English
ISSN
1073-449X
Abstract
RATIONALE:: OBJECTIVES:: METHODS:: MEASUREMENTS AND MAIN RESULTS:: Twenty-four patients with ARDS were included. Increasing PEEP from 5 to 15 cm H2O decreased nonaerated tissue (501 ± 201 to 322 ± 132 grams; P < 0.001) and increased tidal-hyperinflation (0.41 ± 0.26 to 0.57 ± 0.30%; P = 0.004) in supine. Prone positioning further decreased nonaerated tissue (322 ± 132 to 290 ± 141 grams; P = 0.028) and reduced tidal hyperinflation observed at PEEP 15 in supine patients (0.57 ± 0.30 to 0.41 ± 0.22%). Cyclic recruitment/derecruitment only decreased when high PEEP and prone positioning were applied together (4.1 ± 1.9 to 2.9 ± 0.9%; P = 0.003), particularly in patients with high lung recruitability. CONCLUSIONS