학술논문
Abstract 20074: Intracardiac Devices Like Permanent Pacemakers or Cardioverter-Defibrillators Do Not Increase Stroke Risk in Patients With Patent Foramen Ovale
Document Type
Academic Journal
Author
Assar, Manijeh; Sultan, Michael; Gulati, Martha; Al Rabadi, Salem; Agarwal, Sumit; Flores, Erica; Habib, Adnan; Bhardwaj, Supriya; Sridhara, Srilekha; Amabile, Orazio; Tasset, Mark; Gellert, George; Villareal-Argente, Vidette; Kelley, Claire; Jasser, Zuhdi; Kusne, Sharon; Morris, Michael; Byrne, Timothy; Su, Wilbur; Fang, Kenith; Pershad, Ashish; Verma, Divya Ratan
Source
Circulation. Nov 14, 2017 136(Suppl_1 Suppl 1):A20074-A20074
Subject
Language
English
ISSN
0009-7322
Abstract
Hypothesis: To evaluate the risk of stroke in patients with known patent foramen ovale (PFO) undergoing implantation of intracardiac devicesBackground: The risk of stroke in patients with known PFO undergoing implantation of intracardiac devices like permanent pacemaker (PPM) or implantable cardioverter-defibrillator (ICD) is not knownMethods: We retrospectively identified all consecutive patients (n= 7893) with PFO within a large health care network of hospitals with common electronic medical records. Patients who underwent intracardiac device (PPM/ICD) implantation were included in the device group (n= 367) and rest in no-device group (n=7526). Patients were followed for up to 10 years.Results: In unadjusted analysis, 1636 (21.7%) patients in no-device group and 163 (44.4%) patients in device group had a stroke in follow up (HR 2.70, 95% CI 2.26- 3.23, p<0.001; Figure 1). In adjusted multivariate analysis, the risk of having a stroke was similar for both groups (HR 0.93, 95%CI 0.72- 1.12; p= 0.55, after adjusting for baseline characteristics including age, gender, diabetes, congestive heart failure, prior stroke and hypertension).Conclusion: Patients with known patent foramen ovale who undergo an intracardiac device (PPM/ICD) implantation have a similar risk of stroke compared to those without the intracardiac device.