부산대학교 도서관

PURPOSE:: To investigate the utility of optical coherence tomography angiography (OCTA) for the detection of inflammatory choroidal neovascularization (iCNV) and monitoring their response to treatment. METHODS:: A retrospective review of patients with a diagnosis of uveitis and associated iCNV with active exudation was performed. Active iCNV was determined by spectral domain-OCT and/or fluorescein angiogram. Spectral domain-OCTA outer retina to choriocapillaris (ORCC) slabs were evaluated for the presence of iCNV. Follow-up OCTA images were qualitatively assessed to determine if regression of iCNV occurred following treatment. RESULTS:: Thirteen eyes of 12 patients were included. The etiologies of uveitis included punctate inner choroidopathy (n=4), multifocal choroiditis (n=2), presumed sarcoid uveitis (n=2), tuberculous choroiditis (n=1), birdshot chorioretinopathy (n=1), syphilitic uveitis (n=1), serpiginous choroiditis (n=1) and idiopathic panuveitis (n=1). iCNV was detected on en face OCTA in 10/13 eyes (76.9%). Following iCNV treatment, en face OCTA demonstrated complete regression of iCNV in 5/10 eyes (50%), partial regression in 2/10 eye (20%), and no regression in 3/10 eyes (30%). CONCLUSIONS:: OCTA is an effective modality for detecting iCNV and could provide detailed visualization regarding location, morphologic structure, and flow of the iCNV, as well as its response to therapy.