학술논문

Heterogeneous propagation of spreading depolarizations in the lissencephalic and gyrencephalic brain
Document Type
Academic Journal
Source
Journal of Cerebral Blood Flow & Metabolism. Jul 01, 2017 37(7):2639-2643
Subject
Language
English
ISSN
0271-678X
Abstract
In the recently published article, “Heterogeneous incidence and propagation of spreading depolarizations,” it is shown, in vivo and in vitro, how KCl-induced spreading depolarizations in mouse and rat brains can be highly variable, and that they are not limited, as once thought, to a concentric, isotropic, or homogenous depolarization wave in space or in time. The reported results serve as a link between the different species, and this paper contributes to changing the way in which SD expansion is viewed in the lissencephalic brain. Here, we discuss their results with our previous observations made in the gyrencephalic swine brain, in computer simulations, and in the human brain.