부산대학교 도서관

PURPOSE OF STUDY: Preterm as well as term infants admitted in the Neonatal Intensive Care Unit (NICU) undergoing intubation may have high rates of adverse events. There are limited studies on the factors contributing towards adverse events in these infants. This study aims to identify factors that correlate with adverse events associated with intubation. METHODS USED: A retrospective chart review was conducted by collecting data through the NICU database and medical records from infants admitted to the NICU who had intubations performed from January 2014 to June 2016. The primary outcome was to identify intubations with adverse events, and associated variables including number of intubation attempts, personnel performing intubations and medications received prior to intubation. The results were analysed using IBM SPSS statistical software version 24. SUMMARY OF RESULTS: Out of 178 infants intubated during the study period, 44 (24.7%) infants had adverse events. Frequency of adverse events was similar in the infants irrespective of where intubation was performed; delivery room vs NICU. The procedures on infants requiring more than 1 intubation attempt were significantly associated with adverse events (38.1% vs 12.4%; p<0.001). The older infants by chronological age (mean 16 days vs 7 days) were more likely to have an adverse event during intubation than younger ones (p=0.036). Premedication for intubation had no correlation with adverse events. The common adverse events are included in the table with percentages of each event. CONCLUSIONS: Almost a quarter of the NICU infants intubated suffered at least one adverse event at the time of intubation. More than a third of the adverse events consisted of cardiopulmonary resuscitation. Multiple attempts and older age of infant were the most common associations.(Table is included in full-text article.)