학술논문

Mechanisms of bacterial pathogenicity
Document Type
Academic Journal
Source
Postgraduate Medical Journal. Apr 01, 2002 78(918):216-224
Subject
Language
English
ISSN
0032-5473
Abstract
Pathogenic bacteria utilise a number of mechanisms to cause disease in human hosts. Bacterial pathogens express a wide range of molecules that bind host cell targets to facilitate a variety of different host responses. The molecular strategies used by bacteria to interact with the host can be unique to specific pathogens or conserved across several different species. A key to fighting bacterial disease is the identification and characterisation of all these different strategies. The availability of complete genome sequences for several bacterial pathogens coupled with bioinformatics will lead to significant advances toward this goal.