부산대학교 도서관

Introduction: Preservation of cardiovascular health (CVH) across the lifespan is essential to reducing cardiovascular disease burden. Greater knowledge of the relationship between neighborhood level deprivation and CVH in youth is needed.Hypothesis: We hypothesized that worse socio/environmental deprivation is associated with poor/intermediate CVH status in adolescents.Methods: Data from 2009-2019 were extracted from PEDSnet (a PCORI-funded network of pediatric health data). We modeled the relationship between CVH and neighborhood deprivation. National Area Deprivation Index values (ADI; scaled 1-100) were coded into PEDSnet and divided into tertiles (ADI<25=best, 25-52, >52=worst) for analysis. CVH status was scored from a subset of available AHA Life’s Essential 8 (LE8) scores including blood pressure, blood glucose, blood cholesterol, body mass index, smoking/tobacco exposure, and sleep. Overall CVH scores were derived as the average of the sum of the individual scores. Univariate and multivariate analyses were performed. SAS 9.4 was used (p<0.05).Results: Data from 122,177 youth, 13-17 years old were analyzed. 51% were female, 24% lived in neighborhoods with ADI <25; 35% lived in neighborhoods with ADI >52. 58% were non-Hispanic white and 22% non-Hispanic Black. According to a multivariate logistic model, ADI > 52 was associated with a 48% greater odds of poor/intermediate CVH status compared to ADI <25 (Figure). Female sex, ethnic-race categories of Non-Hispanic White and Other, as well private or other forms of non-public insurance coverage were associated with a lower odds of intermediate/poor CVH (Table). Interaction terms for age, ADI, race and ethnicity were not significant.Conclusions: Higher neighborhood deprivation is associated with poor/intermediate CVH status. We recommend greater attention to preserving CVH status within high deprivation communities to preserve and promote CVH status across the lifespan.