학술논문

Magnetic resonance imaging and transvaginal ultrasound for determining fibroid burden: implications for research and clinical care
Document Type
Academic Journal
Source
American Journal of Obstetrics and Gynecology. May 01, 2009 200(5):537e1-537e7
Subject
Language
English
ISSN
0002-9378
Abstract
OBJECTIVES:: To compare magnetic resonance and ultrasound imaging for uterine fibroid measurement. STUDY DESIGN:: Eighteen women undergoing hysterectomy for symptomatic fibroids underwent preoperative pelvic ultrasound and magnetic resonance imaging. Resected fibroids were correlated with the images. Weighted κ agreement statistics and Spearman correlations for patient characteristics were calculated. RESULTS:: Magnetic resonance imaging identified 121 of 151 pathologically confirmed fibroids, yielding 91% positive predictive value (95% confidence interval [CI], 85-95) and 80% sensitivity (95% CI, 73-86). Positive predictive value and sensitivity for ultrasound were 97% (95% CI, 89-100) and 40% (95% CI, 32-48), respectively. Mean diameter-equivalent discrepancies between imaging and pathologic measurements were 0.51 ± 0.68 cm for magnetic resonance imaging and 0.76 ± 0.88 cm for ultrasound. κ statistics comparing imaging to pathology showed better agreement for magnetic resonance than ultrasound (κ = 0.60 vs 0.36). The number of fibroids detected by magnetic resonance imaging predicted measurement errors (r = 0.76; P = .0002). CONCLUSION:: Superior sensitivity and minimal measurement discrepancies suggest magnetic resonance imaging may be preferentially used for fibroid assessment in clinical research.