학술논문

Recognizing Complexity of CD8 T Cells in Transplantation
Document Type
Academic Journal
Source
Transplantation. Apr 19, 2024
Subject
Language
English
ISSN
0041-1337
Abstract
The major role of CD8 T cells in clinical and experimental transplantation is well documented and acknowledged. Nevertheless, the precise impact of CD8 T cells on graft tissue injury is not completely understood, thus impeding the development of specific treatment strategies. The goal of this overview is to consider the biology and functions of CD8 T cells in the context of experimental and clinical allotransplantation, with special emphasis on how this cell subset is affected by currently available and emerging therapies.