학술논문
The IntAct molecular interaction database in 2010
Document Type
Academic Journal
Author
Aranda, B.; Achuthan, P.; Alam-Faruque, Y.; Armean, I.; Bridge, A.; Derow, C.; Feuermann, M.; Ghanbarian, A. T.; Kerrien, S.; Khadake, J.; Kerssemakers, J.; Leroy, C.; Menden, M.; Michaut, M.; Montecchi-Palazzi, L.; Neuhauser, S. N.; Orchard, S.; Perreau, V.; Roechert, B.; van Eijk, K.; Hermjakob, H.
Source
Nucleic Acids Research. Jan 01, 2010 38(20103804 Suppl 1):D525-D531
Subject
Language
English
ISSN
0305-1048
Abstract
IntAct is an open-source, open data molecular interaction database and toolkit. Data is abstracted from the literature or from direct data depositions by expert curators following a deep annotation model providing a high level of detail. As of September 2009, IntAct contains over 200.000 curated binary interaction evidences. In response to the growing data volume and user requests, IntAct now provides a two-tiered view of the interaction data. The search interface allows the user to iteratively develop complex queries, exploiting the detailed annotation with hierarchical controlled vocabularies. Results are provided at any stage in a simplified, tabular view. Specialized views then allows ‘zooming in’ on the full annotation of interactions, interactors and their properties. IntAct source code and data are freely available at http://www.ebi.ac.uk/intact.