학술논문
The impact of Asian descent on the incidence of acquired severe aplastic anaemia in children
Document Type
Academic Journal
Source
British Journal of Haematology. Apr 01, 2003 121(1):170-172
Subject
Language
English
ISSN
0007-1048
Abstract
Previous studies have suggested an increased incidence of acquired severe aplastic anaemia in Asian populations. We evaluated the incidence of aplastic anaemia in people of Asian descent, using a well-defined paediatric (0–14 years) population in British Columbia, Canada to minimize environmental factors. The incidence in children of East/South-east Asian descent (6·9/million/year) and South Asian (East Indian) descent (7·3/million/year) was higher than for those of White/mixed ethnic descent (1·7/million/year). There appeared to be no contribution by environmental factors. This study shows that Asian children have an increased incidence of severe aplastic anaemia possibly as a result of a genetic predisposition.