학술논문
Intra-arterial transplantation of HLA-matched donor mesoangioblasts in Duchenne muscular dystrophy
Document Type
Academic Journal
Author
Cossu, Giulio; Previtali, Stefano C; Napolitano, Sara; Cicalese, Maria Pia; Tedesco, Francesco Saverio; Nicastro, Francesca; Noviello, Maddalena; Roostalu, Urmas; Natali Sora, Maria Grazia; Scarlato, Marina; De Pellegrin, Maurizio; Godi, Claudia; Giuliani, Serena; Ciotti, Francesca; Tonlorenzi, Rossana; Lorenzetti, Isabella; Rivellini, Cristina; Benedetti, Sara; Gatti, Roberto; Marktel, Sarah; Mazzi, Benedetta; Tettamanti, Andrea; Ragazzi, Martina; Imro, Maria Adele; Marano, Giuseppina; Ambrosi, Alessandro; Fiori, Rossana; Sormani, Maria Pia; Bonini, Chiara; Venturini, Massimo; Politi, Letterio S; Torrente, Yvan; Ciceri, Fabio
Source
Embo Molecular Medicine. Dec 01, 2015 7(12):1513-1528
Subject
Language
English
ISSN
1757-4676
Abstract
SYNOPSIS: (Figure is included in full-text article.)This study reports a safe, first-in-human mesoangioblast cell therapy to treat Duchenne muscular dystrophy (DMD) in 5 young patients, using a successful preclinical strategy, as an exploratory non-randomized open-label phase I–IIa clinical trial of intra-arterial HLA-matched donor cell transplantation. : This study reports a safe, first-in-human mesoangioblast cell therapy to treat Duchenne muscular dystrophy (DMD) in 5 young patients, using a successful preclinical strategy, as an exploratory non-randomized open-label phase I-IIa clinical trial of intra-arterial HLA-matched donor cell transplantation.(Figure is included in full-text article.)