학술논문
GB virus C infection and B-cell, natural killer cell, and monocyte activation markers in HIV-infected individuals
Document Type
Academic Journal
Author
Source
AIDS. Jul 17, 2013 27(11):1829-1832
Subject
Language
English
ISSN
0269-9370
Abstract
GB virus C (GBV-C), a pan-lymphotropic flavivirus capable of persistent infection, is associated with prolonged survival and reduced T-cell activation in HIV-infected patients. GBV-C was associated with reduced CD56brt/CD16 natural killer cell and monocyte activation, and a trend toward reduced B-cell activation by measuring cell surface activation markers or HIV entry coreceptors. The GBV-C association was independent of HIV viral load. Thus, GBV-C may influence non-T-cell immune activation in individuals with HIV infection.