학술논문
Effect of atorvastatin on hs-CRP in acute coronary syndrome
Document Type
Academic Journal
Author
Source
British Journal of Clinical Pharmacology. Sep 01, 2008 66(3):411-413
Subject
Language
English
ISSN
0306-5251
Abstract
AIMS: To evaluate the effect of a lower dose (20 mg) of atorvastatin on hs-CRP concentrations in patients with ACS. METHODS: Group A (n = 50) patients received atorvastatin 20 mg day for 4 weeks in addition to standard anti-anginal treatment. Group B (n = 50) patients received standard anti-anginal treatment without atorvastatin. RESULTS: hs-CRP concentrations decreased in both groups, but the decrease was greater in group A. The decrease in hs-CRP was also significantly greater in the subgroups of smoking, hypertension and past history of cardiovascular disease with atorvastatin. CONCLUSIONS: The use of a lower dose (20 mg) of atorvastatin can offer an attractive approach for early treatment of patients with ACS.