학술논문

Treatment of severe recalcitrant hidradenitis suppurativa with adalimumab
Document Type
Academic Journal
Source
Journal der Deutschen Dermatologischen Gesellschaft. Feb 01, 2009 7(2):139-141
Subject
Language
English
ISSN
1610-0379
Abstract
SUMMARY: Hidradenitis suppurativa is a chronic inflammatory skin disease featuring inflammatory nodules, fistulas and discharge of secretions in the intertriginous regions. Without therapy the disease is chronic and progressive. The most effective treatment is the radical wide excision of the affected areas. Systemic antibiotics, immunosuppressants, oral retinoids or antiandrogens have limited beneficial effects. TNF-α antagonists may represent a new therapeutic approach for patients suffering from severe hidradenitis suppurativa offering promising positive influence on the disease outcome. In contrast to infliximab and etanercept, there are only few reports describing the use of adalimumab in severe hidradenitis suppurativa. Here we report a case of a patient with severe recalcitrant hidradenitis suppurativa successfully treated with adalimumab.