학술논문

PM10-stimulated airway epithelial cells activate primary human dendritic cells independent of uric acid: Application of an in vitro model system exposing dendritic cells to airway epithelial cell-conditioned media
Document Type
Academic Journal
Source
Respirology. Aug 01, 2014 19(6):881-890
Subject
Language
English
ISSN
1323-7799
Abstract
BACKGROUND AND OBJECTIVE:: METHODS:: RESULTS:: CONCLUSIONS:: SUMMARY AT A GLANCE: We developed and validated a model of airway epithelial cell conditioned media exposure to primary human dendritic cells. Using this model, we then tested the hypothesis that urban particulate matter exposure to airway epithelial cells resulted in production of soluble mediators capable of inducing dendritic cell maturation.