학술논문

Antibodies to 46-kDa retinal antigen in a patient with breast carcinoma and cancer-associated retinopathy
Document Type
Academic Journal
Source
Breast Cancer Research and Treatment. Jul 02, 2008 110(2):269-271
Subject
Language
English
ISSN
0167-6806
Abstract
Cancer-associated retinopathy (CAR) is a rare paraneoplastic syndrome usually associated with small-cell lung carcinoma and serum autoantibodies against recoverin. We report the breast cancer woman with visual impairments and electrophysiological abnormalities characteristic of CAR. Her serum contained high-titer antibodies against α-enolase but not against other retinal proteins. This suggests that anti-enolase antibodies could be responsible for the development of CAR symptoms.