학술논문
Quantitative CMV Antigenemia Correlated With Ophthalmoscopic Screening for CMV Retinitis in AIDS Patients
Document Type
Academic Journal
Source
Ophthalmic Surgery and Lasers. Jan 01, 2001 32(1):81-82
Subject
Language
English
ISSN
1082-3069
Abstract
ABSTRACT.: To assess the efficacy of the cytomegalovirus (CMV) antigen test in detecting the clinical presence of CMV retinitis. A retrospective chart review was conducted on 86 HIV positive patients who underwent dilated fundus exams for CMV retinitis. All patients had a CMV antigen assay performed within three months of their retinal exam. At a level of 45, the antigen test has a sensitivity of 96% in correctly detecting CMV retinitis and a specificity of 90.2%. The negative and positive predictive values of the antigen test were 98.2% and 80%, respectively. CMV antigen blood test provides a useful screening tool in detecting the presence or absence of CMV retinitis. An antigen level less than 45 strongly suggests the absence of retinitis.