학술논문
123I Scan With Whole-Body Retention Measurement at 48 Hours for Simplified Dosimetry Before 131I Treatment of Metastatic Thyroid Cancer
Document Type
Academic Journal
Source
Clinical Nuclear Medicine. Mar 01, 2021 46(3):e151-e153
Subject
Language
English
ISSN
0363-9762
Abstract
ABSTRACT: A previously published model (Atkins) allows for calculation of I maximum tolerated activity on the basis of 48-hour whole-body retention of I on a pretherapy diagnostic scan. Our practice uses iodine I for diagnostic imaging of metastatic thyroid cancer for staging before I therapy, with images typically acquired 24 hours after administration of the radiopharmaceutical. We explored the feasibility of an additional I whole-body scan and retention measurement at 48 hours, with application of the model to estimate maximum tolerated activity of radioiodine before I treatment of metastatic thyroid cancer.