학술논문
Complete Genome Sequence of the Methanogenic Archaeon, Methanococcus jannaschii
Document Type
Academic Journal
Author
Bult, Carol J.; White, Owen; Olsen, Gary J.; Zhou, Lixin; Fleischmann, Robert D.; Sutton, Granger G.; Blake, Judith A.; FitzGerald, Lisa M.; Clayton, Rebecca A.; Gocayne, Jeannine D.; Kerlavage, Anthony R.; Dougherty, Brian A.; Tomb, Jean-Francois; Adams, Mark D.; Reich, Claudia I.; Overbeek, Ross; Kirkness, Ewen F.; Weinstock, Keith G.; Merrick, Joseph M.; Glodek, Anna; Scott, John L.; Geoghagen, Neil S. M.; Weidman, Janice F.; Fuhrmann, Joyce L.; Nguyen, Dave; Utterback, Teresa R.; Kelley, Jenny M.; Peterson, Jeremy D.; Sadow, Paul W.; Hanna, Michael C.; Cotton, Matthew D.; Roberts, Kevin M.; Hurst, Margaret A.; Kaine, Brian P.; Borodovsky, Mark; Klenk, Hans-Peter; Fraser, Claire M.; Smith, Hamilton O.; Woese, Carl R.; Venter, J. Craig
Source
Science. Aug 23, 1996 273(5278):1058-1073
Subject
Language
English
ISSN
0036-8075
Abstract
The complete 1.66-megabase pair genome sequence of an autotrophic archaeon, Methanococcus jannaschii, and its 58- and 16-kilobase pair extrachromosomal elements have been determined by whole-genome random sequencing. A total of 1738 predicted proteincoding genes were identified; however, only a minority of these (38 percent) could be assigned a putative cellular role with high confidence. Although the majority of genes related to energy production, cell division, and metabolism in M. jannaschii are most similar to those found in Bacteria, most of the genes involved in transcription, translation, and replication in M. jannaschii are more similar to those found in Eukaryotes.