학술논문
5′UTR +24T>C CR2 is not associated with nasopharyngeal carcinoma development in the North Region of Portugal
Document Type
Academic Journal
Author
Source
Oral Diseases. May 01, 2016 22(4):280-284
Subject
Language
English
ISSN
1354-523X
Abstract
OBJECTIVE: METHODS: RESULTS: The genotype distribution was 62.2% TT, 34.2% TC and 3.6% CC for NPC patients; and 65.0%, 30.6% and 4.4%, respectively, for controls. Our study showed no statistical association between the genotype distribution in controls and all types of NPC (P = 0.717); nevertheless, the analysis showed statistically significant differences (P = 0.038) regarding cases with well- or moderately differentiated types of NPC suggesting that +24CC/CT genotypes are associated with increased risk (OR = 4.16; 95% CI 1.28–15.7; P = 0.016). CONCLUSIONS