학술논문
Nationally Certified Stroke Centers Outperform Self-Attested Stroke Centers in the Florida Stroke Registry
Document Type
Academic Journal
Author
Marulanda, Erika; Bustillo, Antonio; Gutierrez, Carolina M.; Rose, David Z.; Jameson, Angus; Gardener, Hannah; Alkhachroum, Ayham; Zhou, Lili; Ying, Hao; Dong, Chuanhui; Foster, Dianne; Hanel, Ricardo; Mehta, Brijesh; Mokin, Maxim; Mueller-Kronast, Nils; Landreth, Mark; Sand, Charles; Romano, Jose G.; Rundek, Tatjana; Asdaghi, Negar; Sacco, Ralph L.
Source
Stroke. Mar 01, 2023 54(3):840-847
Subject
Language
English
ISSN
0039-2499
Abstract
BACKGROUND:: The Florida Stroke Act, signed into law in 2004, set criteria for Comprehensive Stroke Centers (CSC). For a set time period, Florida hospitals were permitted to either receive national certification (NC) or could self-attest (SA) as fulfilling CSC criteria. The aim of this project was to evaluate the quality of ischemic stroke care in NC versus SA stroke centers in Florida, using well-known, guideline-driven ischemic stroke outcome metrics. METHODS:: A total of 37 CSCs (74% of Florida CSCs) in the Florida Stroke Registry from January 2013 through December 2018 were analyzed, including 19 SA CSCs and 18 NC (13 CSCs and 5 Thrombectomy-Capable Stroke Center). Hospital- and patient-level characteristics and stroke metrics were evaluated, adjusting for demographics, medical comorbidities, and stroke severity. RESULTS:: A total of 78 424 acute ischemic stroke cases, 36 089 from SA CSCs and 42 335 from NC CSC/Thrombectomy-Capable Stroke Centers were analyzed. NC centers had older patients (73 [61–83] versus 71 [60–81]; P<0.001) with more severe strokes (median National Institutes of Health Stroke Scale score of 5 versus 4; P<0.001). NC had higher intravenous tissue-type plasminogen activator utilization (15% versus 13%; P<0.001), endovascular treatment (10% versus 7%; P<0.001) and faster median door-to-computed tomography (23 minutes [11–73] versus 31 [12–78]; P<0.001), door-to-needle (37 minutes [26–50] versus 45 [34–58]; P<0.001) and door-to-puncture times (77 minutes [50–113] versus 93 [62–140]; P<0.001). In adjusted analysis, patients arriving to NC hospitals by 3 hours were more likely to get intravenous tissue-type plasminogen activator in the 3- to 4.5-hour window (adjusted odds ratio, 1.87 [95% CI, 1.30–2.68]; P=0.001) and more likely to be treated with intravenous tissue-type plasminogen activator within 45 minutes (adjusted odds ratio, 1.61 [95% CI, 1.04–2.50]; P=0.04) compared with SA CSCs. CONCLUSIONS:: Among Florida-Stroke Registry CSCs, acute ischemic stroke performance and treatment measures at NC centers are superior to SA CSCs. These findings have implications for stroke systems of care in Florida and support legislation updates requiring NC and removal of SA claims.