부산대학교 도서관

At the start of the interview Sir William Paton, professor of Pharmacology at Oxford 1959-84 talks about his childhood and education, and the decision to study medicine at Oxford. He speaks of his tutors at New College - the physiologist RS Creed and the theologian RH Lightfoot - and organ lessons with Sydney Watson. Sir William then discusses his clinical studies at University College Hospital from 1939: a year in Cardiff to avoid heavy bombing, the influence of Max Rosenheim, the experience of being a medical student in London during the war. House jobs followed, then a bout of pneumonia, which he had already had several times, ruled out residential clinical positions, so he worked for a year as a pathologist at the TB sanatorium at Midhurst. Next, Sir William reflects on his work at the National Institute of Medical Research from 1944 to 1952. He acknowledges the effective leadership of GL Brown and FC Macintosh. Early physiological research into diving problems, including decompression sickness and the escape from submarines by free ascent, his move to pharmacology - working on methonium compounds with Eleanor Zaimis, and collaborating with anaesthetist Geoffrey Organe - and the impact of the move to Mill Hill in 1949 on the atmosphere at the Institute, are outlined. Then there is discussion of developments in British pharmacology: the low status of the discipline for many years, the influence of JH Gaddum, and the early years of the British Society of Pharmacology. In 1952 Sir William moved to UCH as reader in applied pharmacology. He talks of his teaching, which attempted to bridge the gap between basic preclinical pharmacology and therapeutics, and his research on histamine distribution and, with John Thompson, on porphobilinogen. Next, Sir Wiliam reflects on his five years as the first Vandervell professor of pharmacology at the Royal College of Surgeons. He outlines the challenges of setting up new department, developing a laboratory and building up a team