부산대학교 도서관

Trivalent‐phosphorus‐containing molecules, especially phosphines, are currently used as a ligand in transition metal catalysis. Historically, it was thought that phosphine CH bonds were almost not reactive, but recent examples have demonstrated that it is possible to functionalize them easily under proper conditions. These methods use various Pd, Ir, Ru, and Rh transition metals and native P(III)‐atom as directing groups allowing the regioselective late‐stage functionalization of phosphine ligands. Interestingly, some modified phosphines have outperformed their parent ones in transition metal cross‐coupling reactions. This article summarized the different approaches for the P(III)‐directed CH bond functionalizations.