부산대학교 도서관

This chapter analyzes Neisseria gonorrhoeae, which reportedly caused 583,405 infections in the United States in 2018, an increase of 63% since 2014. Gonococci attach primarily to columnar or cuboidal epithelial cells via pili and outer membrane proteins; the gonococcus penetrates between and through the cells to submucosal areas, where it elicits a neutrophilic host response. This chapter investigates the clinical spectrum of primary infection with N. gonorrhoeae, which mirrors that of Chlamydia trachomatis. The authors also discuss acute urethritis, which manifests as some combination of urethral discharge and dysuria and is known as the most common presentation of gonococcal disease in men.