부산대학교 도서관

Pediatric low-grade gliomas (PLGGs) are the most common subgroup of central nervous system (CNS) tumors in childhood. These tumors have a good prognosis, especially when they are completely resectable. Traditional cytotoxic chemotherapy and radiation therapy have proved to be effective in many unresectable cases, but careful attention to age of the patient and location of the tumor must be considered before embarking on a treatment plan. More recently, targeted therapy with either BRAF or MEK inhibitors has shown promising efficacy, and these agents are likely to play an increasing role in treatment of these patients moving forward.