부산대학교 도서관

Typhlitis is a life-threatening disease of bowel, mainly ileum or cecum, complicated in the immunocompromised hasts. Recently we experienced four cases of typhlitis in leukemic patients following cytotoxic chemotherapy. All the patients were diagnosed as acute myelogenous leukemia and received cytotoxic chemotherapy followed by granulocytopenia. They mainly showed fever, abdominal pain, and diarrhea. In one case, he suffered from intestinal obstruction. Abdominal CT showed diffuse thickening of ileocecal region or ascending colon. Stool culture revealed Staphylococcus aureus in two cases and Entercoccus species in one case. Staphylococcus aureus was isolated from blood culture in one case. They were managed medically and three out of four cases survived.