학술논문
융모양막염 산모로부터 출생한 극소저체중아에서 발생한 선천성 피부 칸디다증 1예
A Case of Congenital Cutaneous Candidiasis in Very Low Birth Weight Infant with Maternal Chorioamnionitis
A Case of Congenital Cutaneous Candidiasis in Very Low Birth Weight Infant with Maternal Chorioamnionitis
Document Type
Article
Author
김경민 / Kyungmin Kim; 김도연 / Doyeon Kim; 홍동균 / Dongkyun Hong; 정경은 / Kyung Eun Jung; 서영준 / Young-joon Seo; 장미영 / Meayoung Chang; 이영 / Young Lee
Source
대한피부과학회지 / Korean Journal of Dermatology. Jan 31, 2023 61(1):52
Subject
Language
Korean
ISSN
0494-4739
Abstract
Congenital cutaneous candidiasis (CCC) is a rare disease caused by Candida spp. that occurs within the first six days of life. Its exact pathogenesis remains unclear; however, the suspected pathomechanisms include maternal vulvovaginal candidiasis and ascending infections. A preterm, 1,550-g male infant presented with generalized maculopapules and pustules on his whole body. The patient’s mother had undergone cervical cerclage at a gestational age (GA) of 29 weeks due to an incompetent internal os of the cervix. The pregnancy was terminated at GA 37-week because the mother developed chorioamnionitis. We performed a potassium hydroxide microscopic examination, skin biopsy, and fungal culture test on the baby. Microscopic examination of the skin scrapings revealed pseudohyphae with yeasts, and Candida albicans was identified in the culture test. Maternal placental biopsy revealed fungal organisms, and the baby was diagnosed with CCC due to an ascending infection. The skin lesions completely disappeared after intravenous liposomal amphotericin B treatment. (Korean J Dermatol 2023;61(1):52∼56)