학술논문

Neuroendocrine Regulation of Energy Metabolism
Document Type
Article
Source
Endocrinology and Metabolism(구 대한내분비학회지). Dec 01, 2012 27(4):268
Subject
Ghrelin
Glucose
Hunger
Hypothalamus
Leptin
Language
Korean
ISSN
2093-596X
Abstract
Significant advancements have been made in the past century regarding the neuronal control of feeding behavior and energy ex-penditure. The effects and mechanisms of action of various peripheral metabolic signals on the brain have become clearer. Molecu-lar and genetic tools for visualizing and manipulating individual components of brain homeostatic systems in combination with neuroanatomical, electrophysiological, behavioral, and pharmacological techniques have begun to elucidate the molecular and neuronal mechanisms of complex feeding behavior and energy expenditure. This review article highlights some of these advance-ments that have led to the current understanding of the brain`s involvement in the acute and chronic regulation of energy homeo-stasis. (Endocrinol Metab 27:268-273, 2012)