학술논문
양식 넙치에서 연쇄구균 혼합백신 접종 후 항체가 변화 조사
Development of antibodies after combination Streptococcus iniae and Streptococcus parauberis of commercial vaccine injection in olive flounder (Paralichthys olivaceus) in farm
Development of antibodies after combination Streptococcus iniae and Streptococcus parauberis of commercial vaccine injection in olive flounder (Paralichthys olivaceus) in farm
Document Type
Article
Author
한현자 / Hyun-ja Han; 이덕찬 / Deok Chan Lee; 김수진 / Soo-jin Kim; 김태호 / Tae-ho Kim; 정선명 / Sun-myoung Jeong; 김재휘 / Jae-hwi Kim; 최윤재 / Yoon-jea Choi; 조경용 / Kyeong-yong Cho; 조미영 / Mi-young Cho
Source
한국어병학회지 / Jouranl of Fish Pathology. Jun 30, 2024 37(1):71
Subject
Language
Korean
English
English
ISSN
1226-0819
Abstract
Streptococcosis, caused by Streptococcus iniae and Streptococcus parauberis is an important bacterial disease that affects in olive flounder in Korea. In Korea, multivalent bacterial vaccines are used to prevent streptococcal diseases in aquaculture. In this study, commercial vaccines containing formalin- inactivated bacterial cells of S. iniae and S. parauberis were administered at six fish farms and one unvaccinated fish farm were designated for investigation (Wando; 4 sites and Jeju; 3 sites). Blood was collected from vaccinated and unvaccinated olive flounders, and titers of antibodies against S. iniae and S. parauberis in serum were analyzed using ELISA. After a one shot vaccination in the farms at Jeju (farm A) and Wando (farm D), the proportion of individuals with specific antibodies against S. parauberis OD values of 0.4 or higher was 60% and 53.5%, respectively. But after booster vaccination, the proportion of individuals with serum OD values of 0.4 or higher was higher substantially increased to 96.6% (farm A) and 100% (farm D). The levels of S. parauberis specific antibodies of olive flounder were increased after vaccination in three fish farms (farm D, E, and F), but not S. iniae specific antibodies.