학술논문
실외 대기오염물질이 소아청소년 알레르기비염에 미치는 영향
Effects of outdoor air pollution on children with allergic rhinitis
Effects of outdoor air pollution on children with allergic rhinitis
Document Type
Article
Author
성명순 / Myongsoon Sung; 김민지 / Minji Kim; 김현희 / Hyun Hee Kim; 나영호 / Yeong-ho Rha; 박양 / Yang Park; 박용민 / Yong Mean Park; 신윤호 / Youn Ho Sheen; 염혜영 / Hye Yung Yum; 이경석 / Kyung Suk Lee; 이용주 / Yong Ju Lee; 전윤홍 / Yoon Hong Chun; 지혜미 / Hye Mi Jee; 최봉석 / Bong Seok Choi; 최선희 / Sun Hee Choi; 김효빈 / Hyo-bin Kim
Source
Allergy asthma & respiratory disease. Jul 30, 2022 10(3):139
Subject
Language
Korean
ISSN
2288-0402
Abstract
The global worsening of air pollution has decreased the quality of life. Air pollutants can induce oxidative stress, epigenetic changes, and alterations to microRNA expression in the airway and skin, leading to immune dysregulation. Previous epidemiological studies suggest a strong association between outdoor environmental pollution and childhood allergic disease, especially allergic rhinitis (AR). Moreover, traffic-related air pollution has increased the severity and incidence of AR, and heavy traffic has been associated with an increased prevalence of AR. Thus, this review aimed to define outdoor environmental pollution and clarify the mechanisms by which air pollutants aggravate AR. In addition, we performed a systematic review and meta-analysis to summarize the findings of several domestic and international epidemiological and clinical studies about the effects of air pollution on AR in children. (Allergy Asthma Respir Dis 2022;10:139-144)