학술논문
한국 초,중,고등학생 알레르기비염의 전국 유병률과 위험 인자에 대한 분석
The prevalence and risk factors of allergic rhinitis from a nationwide study of Korean elementary, middle, and high school students
The prevalence and risk factors of allergic rhinitis from a nationwide study of Korean elementary, middle, and high school students
Document Type
Article
Author
김영호 / Yeongho Kim; 서주희 / Ju Hee Seo; 권지원 / Ji Won Kwon; 이은 / Eun Lee; 양송이 / Song I Yang; 조현주 / Hyun Ju Cho; 하미나 / Mina Ha; 범은애 / Eunae Burm; 이기재 / Kee Jae Lee; 김환철 / Hwan Cheol Kim; 임신예 / Sinye Lim; 강희태 / Hee Tae Kang; 손미아 / Mia Son; 김수영 / Soo Young Kim; 정해관 / Hae Kwan Cheong; 김유미 / Yu Mi Kim; 오경재 / Gyung Jae Oh; 사공준 / Kong Joon Sa; 이철갑 / Chul Gab Lee; 김수진 / Sue Jin Kim; 백영욱 / Yong Wook Beak; 홍수종 / Soo Jong Hong
Source
Allergy asthma & respiratory disease. Jul 30, 2015 3(4):272
Subject
Language
Korean
ISSN
2288-0402
Abstract
Purpose: We investigated the prevalence and risk factors of allergic rhinitis (AR), nationwide in random children and adolescents of Korea. Methods: A modified International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire survey was done in 1,820 children from elementary, middle, and high school nationwide in Korea. The subjects were selected by the stratifying sampling method by school grade and five regions. Current AR was defined as having AR symptoms during the last 12 months with a history of physician-diagnosed AR. Skin prick tests for 18 common allergens were performed. Results: The number of males was 945, and that of females was 875. The mean age of the patients was 12.61±3.40 years. The prevalence of current AR and atopic current AR were 29.0% and 18.7%, respectively. Risk factors for current AR were male (adjusted odds ratio [aOR], 1.486; 95% confidence interval [CI], 1.189.1.856), family history of paternal AR (aOR, 3.208; 95% CI, 2.460.4.182), family history of maternal AR (aOR, 3.138; 95% CI, 2.446.4.025), antibiotic use in infancy (aOR, 1.547; 95% CI, 1.228.1.949), mold exposure during infancy (aOR, 1.416; 95% CI, 1.103.1.819), mold exposure during the last 12 months (aOR, 1.285; 95% CI, 1.012.1.630), and sensitization on skin prick tests (aOR, 2.596; 95% CI, 2.055.3.279). Risk factors for atopic current AR were the same as those of current AR, whereas breast-milk feeding (aOR, 0.720; 95% CI, 0.530.0.976) was a protective factor. Sensitized allergens as risk factors for current AR were Dermatophagoides pteronyssinus, Dermatophagoides farina, ragweed, mugwort, oak, alder, birch, Japanese hop, cat, and dog. Conclusion: The prevalences of current AR and atopic current AR were 29.0% and 18.7%, respectively. Male, sex parental AR, antibiotic use in infancy, mold exposure during the last 12 months, mold exposure during infancy, and atopic sensitization were risk factors for current AR. Breast-milk feeding was a protective factor for atopic current AR. Aeroallergen sensitization was an important risk factor for AR. (Allergy Asthma Respir Dis 2015;3:272-280)