부산대학교 도서관

Background: Atherosclerosis and endothelial dysfunction are main pathological event for developing ischemic heart disease. It is damaged that the endothelial produced vasoactive and antithrombotic agents in the process of atherosclerosis and endothelial dysfunction occurs. Microalbuminuria is an indicator for the endothelial dysfunction. In this study, it was investigated the relationship between microalbuminuria and acute coronary syndrome. Methods: This study was consisted up 35 acute coronary syndrome patients without diabetes mellitus. Metabolic parameters and microalbuminuria in 24 hours urinary collection of the patients were analyzed. Above 30 mg/dl daily urinary albumin excretion was described as microalbuminuria (30-300 mg/dl). Microalbuminuric patients were followed up for one year. Patients parameters` mean and standart deviation were calculated. It was statiscically meaningful, p<0,05. Results: 27 male and 8 female, total 35 patients were added in the study group. It was determinated that the mortality and reinfarctus were higher in microalbuminuric patient. 3 reinfarctus and 3 mortality were determinated in normoalbuminuric patients. Fasting triglycerid and homocystein levels were lower in microalbuminuric patients. Conclusions: It was demonstrated that the prognostic signifi cance of microalbuminuria in the acute coronary syndrome patients for one year follow up.