학술논문

2020 Seoul Consensus on the Diagnosis and Management of Gastroesophageal Reflux Disease
Document Type
Article
Source
Journal of Neurogastroenterology and Motility. Oct 31, 2021 27(4):453
Subject
Diagnosis
Gastroesophageal reflux disease
Guideline
Meta-analysis
Treatment
Language
English
ISSN
2093-0879
Abstract
Based on a meta-analysis of 19 estimated acid-exposure time values in Asians, the reference range upper limit for esophageal acid exposure time was 3.2% (95% confidence interval, 2.7-3.9%) in the Asian countries. Esophageal manometry and novel impedance measurements, including mucosal impedance and a post-reflux swallow-induced peristaltic wave, are promising in discrimination of GERD among different reflux phenotypes, thus increasing its diagnostic yield. We also propose a long-term strategy of evidence-based GERD treatment with proton pump inhibitors and other drugs. (J Neurogastroenterol Motil 2021;27:453-481)