부산대학교 도서관

Background: Among the risk factors associated with coronary artery disease (CAD), hyperlipidemia is one of the most important. In recent years, the incidence of CAD is increasing in Korean population, being attributed to increasing longevity, the changes in diet and economical conditions. The study was designed for establishing normal adult va1ues of serum lipids in Korean workers. Methods: Serum total cholesterol (TC) and triglyceride (TG) were measured by the enzymatic method and their levels were analysed in relation to different working areas and conditioins in 18518 males and 360 females, resident in Pohang (11651 males and 360 females) and Kwangyang (6867 males) city, Korea. The study subjects are all workers who were considered to be clinically healthy. Results: Total cholesterol levels of male and female adults in Pohang were 171.2±31.2mg/dl and 166.5±30.7 mg/dl and levels of males in Kwangyang were 163.0±28.9 mg/dl, respectively. The total cholesterol levels of males in Pohang were significantly higher than those of females (p<0.01), and males (p<0.001) in Kwangyang. The total cholesterol levels gradually increased significantly with age (twenties through forties) in males in both areas. Serum triglyceride levels of males in Pohang were 124.4±70.7mg/dl and also increased significantly with age (twenties through thirties), respectively. Serum total cholesterol and triglyceride levels of male employees above the level of chief clerk were significantly higher than those of employees below the level of chief clerk (p<0.001). Serum total cholesterol and triglyceride levels of male white-collar workers were significantly higher than those of male blue-collar workers (p<0.001, p<0.01). Serum total cholesterol levels of male nonshift workers were significantly higher than those of male shift workers (p<0.001). Serum total cholesterol and triglyceride levels showed a statistically significant elevation with increment of body weight in male (p<0.001). Serum cholesterol levels of male heavy drinkers (1902 cases, 165.7±29.5 mg/dl) were significantly higher than those of light drinkers (4400 cases, 161.8±28.4 mg/dl) (p<0.001). Serum total cholesterol levels of male heavy smokers (252 cases, 169.9±32.0 mg/dl) were significantly higher than those of male non-smokers (2128 cases, 163.4±28.7mg/dl) (p<0.01), or male light smokers (4487 cases, 162.4±28.8 mg/dl) (p<0.001). Serum total cholesterol levels of male heavy drinkers and heavy somkers (115 cases, 170.5±34.1 mg/dl) were significantly higher than those of non-drinkers and non-smokers (358 cases, 161.1±29.2 mg, dl) (p<0.01), or than those of light drinkers and 1ght smokers (2893 cases, 161.1±28.5 mg/dl) (p<0.01). But there were no significant differences in cholesterol levels between all of drinkers and non-drinkers, between all of smokers and non-smokers. Conclusion: In conclusion, total cholesterol and triglyceride levels of our study subjects are largely influenced by age, sex, body weight, a residential district, working conditions, and weakly influenced by alchol drinking and smoking habits.