학술논문

Major clinical research advances in gynecologic cancer in 2023: a tumultuous year for endometrial cancer
Document Type
Article
Source
Journal of Gynecologic Oncology (JGO). Mar 01, 2024 35(2):1
Subject
Gynecologic Neoplasms
Survival
Immunotherapy
Molecular Targeted Therapy
Poly
ADP-Ribose
Polymerase Inhibitor
Antibodies
Monoclonal
Immunoconjugates
Language
Korean
English
ISSN
2005-0380
Abstract
In the 2023 series, we summarized the major clinical research advances in gynecologic oncology based on communications at the conference of Asian Society of Gynecologic Oncology Review Course. The review consisted of 1) Endometrial cancer: immune checkpoint inhibitor, antibody drug conjugates (ADCs), selective inhibitor of nuclear export, CDK4/6 inhibitors WEE1 inhibitor, poly (ADP-ribose) polymerase (PARP) inhibitors. 2) Cervical cancer: surgery in low-risk early-stage cervical cancer, therapy for locally advanced stage and advanced, metastatic, or recurrent setting; and 3) Ovarian cancer: immunotherapy, triplet therapies using immune checkpoint inhibitors along with antiangiogenic agents and PARP inhibitors, and ADCs. In 2023, the field of endometrial cancer treatment witnessed a landmark year, marked by several practice-changing outcomes with immune checkpoint inhibitors and the reliable efficacy of PARP inhibitors and ADCs.