학술논문

Concise Review: Applicability of High-resolution Manometry in Gastroesophageal Reflux Disease
Document Type
Article
Source
Journal of Neurogastroenterology and Motility. Oct 31, 2022 28(4):531
Subject
Diagnosis
Esophageal motility disorders
Gastroesophageal reflux
Manometry
Phenotype
Language
English
ISSN
2093-0879
Abstract
Manometry, particularly high-resolution manometry is the preferred diagnostic tool used to evaluate esophageal motor function. This investigation is strongly indicated in the setting of dysphagia, but is also useful in gastroesophageal reflux disease (GERD), especially in case of failure of conventional treatment to exclude alternative diagnoses and prior to anti-reflux surgery. Moreover, ineffective esophagogastric junction barrier function and esophageal motor dysfunction are pathophysiological mechanisms in GERD and can be identified by manometry. The recent international guidelines have positioned high-resolution manometry as an important part of functional diagnostic work up in GERD in order to identify the GERD phenotype to guide specific treatment. The proposed manometric identification and measurement is based on the Chicago classification version 4.0 adding with new established metrics for GERD evaluation. (J Neurogastroenterol Motil 2022;28:531-539)