학술논문
면역글로불린 E 매개 계란 알레르기 환자에 대한 경구 면역치료 3예
Three cases of oral immunotherapy for IgE-mediated egg allergy
Three cases of oral immunotherapy for IgE-mediated egg allergy
Document Type
Article
Author
김인성 / Insung Kim; 이보라 / Bo Ra Lee; 경예찬 / Yechan Kyung; 정민영 / Minyoung Jung; 양혜경 / Hea-kyoung Yang; 김민지 / Minji Kim; 이지영 / Ji Young Lee; 김지현 / Jihyun Kim; 안강모 / Kangmo Ahn; 정혜인 / Hye-in Jeong
Source
Allergy asthma & respiratory disease. Jul 30, 2020 8(3):161
Subject
Language
Korean
ISSN
2288-0402
Abstract
Food allergy is an immune-mediated adverse reaction that occurs mainly by food ingestion. Some children with food allergies manifest fatal symptoms like anaphylaxis. Oral immunotherapy (OIT) may offer an effective therapeutic modality for persistent and severe forms of food allergies. We report our experience with OIT in 3 patients with IgE-mediated hen’s egg allergy. Our treatment strategy consists of 1-3 days of initial escalation, 47 to 65 weeks of build-up phase, and 1 year of maintenance phase. Lactobacillus plantarum CJLP133, 1×1010 colony-forming unit/day was taken during OIT. As a result, 1 patient achieved successful desensitization, and 1 patient reached maintenance therapy, but did not obtain desensitization. In addition, 1 patient withdrew from treatment due to anxiety symptoms. Despite the limited number of patients, we experienced and herein presented 3 cases of OIT in egg allergy. More trials of OIT need to be performed as a treatment option in Korean children with food allergies. (Allergy Asthma Respir Dis 2020;8:161-164)