학술논문

호산구 증가증과 연관된 무감정성 갑상선기능항진증 2 예
Two Cases of Apathetic Hyperthyroidism associated with Peripheral Eosinophilia
Document Type
Article
Source
Endocrinology and Metabolism, 20(1), pp.78-83 Feb, 2005
Subject
내과학
Language
ISSN
2093-5978
2093-596X
Abstract
Peripheral eosinophilia is perpetually associated with many disease conditions like asthma, parasitic disease, IL-2 therapy, hypereosinophilic syndrome and eosinophilia/myalgia syndrome. Furthermore, peripheral eosinophilia may also be linked with Graves' disease, which is induced by thyroid-stimulating anti-TSH receptor antibodies and is related to type 2 helper T cell(Th2) predominant condition that is dependent on humoral immunity. In some of the cases of Graves' disease, thyrotoxicosis may induce peripheral eosinophilia associated with relative cortisol deficiency. In our present study, we present a case of two patients who were suffering from Graves' disease without any thyrotoxic symptoms and exhibited increased levels of peripheral eosinophil count. But, the count was observed to decreas in euthyroid state
저자들은 갑상선 중독 증상없이 말초 혈액 내 호산구 증가만으로 갑상선기능항진증을 진단 받은 환자에서 항갑상선제 투여 후 갑상선 기능 호전 및 호산구 수의 감소를 보인 증례를 경험하였기에 문헌 고찰과 함께 이를 보고하는 바이다.