부산대학교 도서관

Our simple technique of polymer/metal-based material preparation produces very promising material, and weoutline that this material can be suitable for the potential wound healing multilayered dressing. In our research we focused onthese main issues: (1) the preparation of silver nanowire-like structures using gallic acid (GA); (2) direct silver nanowire-likestructure crystallization of co-polymer L-lactide and ε-caprolactone (PLCL) electrospun fiber and (3) evaluation of thematerial cytotoxicity on the Vero cell line. Synthesized silver nanowire-like width varied from 30 to 100 nm and thehexagonal particles had sizes from 80 to 300 nm. The detected structures were crystalline cubic silver and were similarlysynthesized during both batch synthesis and direct synthesis on the PLCL fibers. The amount of the silver spread within thefibrous membrane was approximately 1.1 wt. % in the sample, moreover, the silver incorporation had no influence on thepolymer structure, which was confirmed by FTIR measurement. The cytotoxicity testing estimated that cell survivalincreased with decreased concentration of GA and silver in the PLCL matrix and the silver-based sample in 50 % MTTextraction concentration maintained required non-cytotoxic properties.