부산대학교 도서관

Purpose: To compare the refractive outcomes after cataract surgery between patients with and without pseudoexfoliation,and to evaluate the risk factors of refractive error. Methods: Retrospective review of 210 eyes with pseudoexfoliation (study group) and 510 normal eyes (control group) thatunderwent uneventful phacoemulsification with intraocular lens implantation. The study group included pseudoexfoliationsyndrome and pseudoexfoliation glaucoma (PXG) subgroups. The main outcome measure was refractive error, defined as thedifference between the target refraction and postoperative refraction in diopter (D). A refractive error >±1.0 D was identifiedas a large-magnitude refractive error. The frequency of the large-magnitude refractive error was compared between studyand control groups, and also between each subgroup and normal eyes. The factors influencing refractive error were analyzedby logistic regression. Results: There was a significantly higher frequency of a refractive error >± 1.0 D and hyperopic error >1.0 D in the studygroup than in the control group (p = 0.001 and p = 0.003, respectively). In the multivariate logistic regression analysis, PXGand poor preoperative visual acuity were related with a large-magnitude refractive error (p = 0.001 and p = 0.02, respectively)Refractive error >± 1.0 D and hyperopic error >1.0 D were noted more often in PXG eyes that had an intraocular pressurespike >25 mmHg at postoperative first 24 hours (p = 0.01 and p=0.03, respectively). Conclusions: The eyes with pseudoexfoliation were at a high risk for refractive error, especially in the presence of glaucoma. In PXG, the only significant risk factor for refractive error was observed to be the presence of an intraocular pressure spike.