학술논문
Production of a Monoclonal Antibody by Ascites, Hollow Fiber System, and Transgenic Plants for Vaccine Production Using CB.Hep-1 mAb as a Study Case
Document Type
Article
Author
Rodolfo Valdés; Andrés Tamayo; Marcos González; Sigifredo Padilla; Déborah Geada; William Ferro; Lorely Milá; Leonardo Gómez; Rosario Alemán; Alberto Leyva; Cristina García; Otto Mendoza; Tatiana Alvarez; Lamay Dorta; Yanet Villega; Dobián Cecilia; Hasel Aragón; Tatiana González; Maylín La O; Jorge López
Source
Biotechnology and Bioprocess Engineering, 17(1), pp.145-159 Feb, 2012
Subject
Language
English
ISSN
1976-3816
1226-8372
1226-8372
Abstract
Monoclonal antibody (mAb) production methods (ascites, in vitro technologies, transgenic animals, and dicot or monocot transgenic plants; moss, algae) have been improved since they were first developed in 1975. In this study, we illustrate a summary of a study case in which mice, a hollow fiber system, and tobacco transgenic plants were assessed for the production of mAb for vaccine manufacturing and vaccine production.