부산대학교 도서관

Ginseng has been widely studied due to its various therapeutic properties on various diseases such ascardiovascular disease (CVD). Cardiovascular disease has been canonically known to be caused by highlevels of low-density lipoproteins (LDL) in the bloodstream, in addition to the impaired vasodilatoryeffects of cholesterol. However, current research on CVD has revealed a cascade of mechanisms involvinga series of events that contribute to the progression of CVD. Although this has been elucidated andsummarized in previous studies the detailed correlation between platelet aggregation and innate immunity that plays an important role in CVD progression has not been thoroughly summarized. Furthermore, immune cell subtypes also contribute to the progression of plaque formation in the subendothelial layer. Thrombus formation and the coagulation cascade also have a vital role in the progression of atherosclerosis. Hence, in this mini review we aim to elucidate, summarize, and propose thepotent therapeutic effect of ginseng on CVD, mainly on platelet aggregation, plaque formation, andthrombus formation.