부산대학교 도서관

Objectives: Two historical evidence supported the concept of Gamrosu. The first one was Jeho-tang, a selected thirst quencher in Chosun Dynasty and the second one was Saeng- Maek-san, Dongeuibogam’s recommendation as one of the qi-vigorating summer beverages. Gamrosu is a modified fasting therapy beverage which is manufactured from those two prescriptions and the carbohydrates (420.6 kcal/d). A retrospective observational study was conducted to evaluate the clinical outcomes. Methods: Thirty-three cases were reviewed at three local Korean Medical clinics that each site’s participant has finished the modified fasting for 10 consecutive days. Clinical outcomes were reviewed at pre- and post-fasting sessions by retrieving the changes of body composition, blood pressure, blood chemistries & urine tests, and subjective symptoms & fatigue scores. Results: Demographics of the observed participants were 17 of male and 16 of female. Post-Gamrosu session, −6.89% of body weight, −8.97% of body fat mass were reduced with the nutrition indices being improved (P＜0.001). −8.72% of systolic blood pressure, −39.86% of serum triglyceride, −6.75% of fast blood sugar and −8.12% of waist circumference were improved (P＜0.05). The levels of high sensitivity C-reactive protein (−58.34%), CRP (−43.55%) and eosinophil (−21.30%) showed the significant diminished profiles (P＜0.05). Liver/kidney functions and the standard of electrolytes were maintained within normal range in stable manners. The fatigue scale scores indicated significant lower scores. Conclusions: Taken together, obesity-related clinical outcomes after a modified fasting therapy with Gamrosu were sufficiently feasible and the observed findings should be considered for further prospective clinical studies.