부산대학교 도서관

This study was conducted to investigate the residual characteristics and risk assessments of the fungicides dimethomorph and mandipropamid in mandarin. The pesticides were sprayed three times with a dose of 200 L/10 at 1,000 fold dilution for dimethomorph and 2,000 fold dilution for mandipropamid with different treatment days before harvest. The mandarin samples analyzed by liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) and method limits of quantitation (MLOQ) were 0.01 mg/kg of both fungicides. Average recoveries of dimethomorph and mandipropamid in mandarin were good in the range 88.5% to 96.1 and 80.9% to 95.8%, respectively. Residual amounts of dimethomorph and mandipropmid were ranged from 1.45 to 3.06 mg/kg and 0.45 to 1.26 mg/kg, respectively. The residue levels of two fungicides in mandarin tended to increase as spraying closer to the harvest day. Based on the first-order kinetics model, biological half-life were 24.2 days for dimethomorph and 15.6 days for mandipropamid, respectively, indicated shorter half-life compared to dimethomorph. Risk assessments of residual pesticides showed that the risks were less than 0.5% and the safety of the selected pesticides.
본 연구는 감귤 중 살균제 dimethomorph와 mandipropamid의 잔류특성과 위해성을 평가하기 위하여 수행 되었다 . 시험농약인 dimethomorph와 mandipropamid는 수확 전 약제 처리일을 다르게 설정하여 각각 1000배 및 2000배 희석액을 200 L/10 a의 약량으로 3회 살포하였다 . 감귤 시료는 액체크로마토그래피와 결합한 탠덤 질량분석 기(LC-MS/MS)로 분석하였고 분석법상 정량한계 (MLOQ)는 두 살균제 모두 0.01 mg/kg이었다 . 감귤 중 dimethomorph 및 madipropamid의 평균 회수율은 각각 88.5-96.1% 및 80.9-95.8%의 범위로 양호했다 . 감귤 중 dimethomorph 및 madipropamid의 잔류량은 각각 1.45-3.06 mg/kg 및 0.45-1.26 mg/kg이었다 . 감귤 중 두 살균제의 잔류량은 수확일에 가까워질수록 증가하는 경향을 보였다 . First order kinetics model에 따르면 감귤 중 dimethomorph의 반감기는 24.2 일, mandipropamid는 15.6일로 mandipropamid가 dimethomorph의 반감기보다 짧았다 . %ADI (일일섭취허용량 대비 일일섭취추정량 )를 이용한 위해성 평가는 두 살균제 모두 0.5% 미만으로 안전한 수준을 나타냈다 .