학술논문
Measurement of total body water with deuterium oxide Comparison with body fluid volume and standard body weight of maintenance hemodialysis patients, estimated by total body water and lean body mass / 重水による全体水分量の測定
Document Type
Journal Article
Author
Source
日本透析療法学会雑誌 / Journal of Japanese Society for Dialysis Therapy. 1988, 21(12):1151
Subject
Language
Japanese
ISSN
0911-5889
1884-6211
1884-6211
Abstract
The standard body weight (SW) in hemodialysis (HD) patients has been generally calculated using blood pressure, cardio-thoracic ratio (CTR), and so on. However, it is difficult to estimate SW with this method in some HD patients. We measured total body water (TBW) by administration of 99.8% deuterium oxide and calculated the lean body mass (LBM) from the height, body weight (BW), and waist girth. Body fluid volume and SW were estimated from TBW and LBM in HD patients and the results compared with those in normal subjects. In HD patients, TBW/BW was greater than in normal subjects by 3-4% in males and 5-10% in females, respectively. No relationships among CTR, SW and TBW were observed. A TBW/LBM value of >0.78 was suggested to indicate an overhydrated state in HD patients, and the mean TBW/LBM in such patients was 0.757, which was greater than that in normal subjects. Hypotensiòn during HD was induced by excess ultrafitration, regardless of the value of TBW/LBM.