학술논문
A case of PBC-AIH overlap syndrome who developed AIH 8 years after diagnosis of typical PBC / 原発性胆汁性肝硬変の診断8年後に自己免疫性肝炎を合併したPBC-AIH overlap症候群の1例
Document Type
Journal Article
Author
Source
肝臓 / Kanzo. 2009, 50(8):445
Subject
Language
Japanese
ISSN
0451-4203
1881-3593
1881-3593
Abstract
A 41-year-old woman who had been diagnosed as PBC 8 years ago (1999) admitted to our hospital due to general malaise and the elevation of serum transaminase level on December 2007. Liver biopsy showed CNSDC on the first admission (1999). However, it showed interface hepatitis in addition to CNSDC on the second admission (2007). According to the IAHG scoring system, her score was 16 points indicating the probable AIH. Therefore, she was diagnosed as PBC-AIH overlap syndrome. We started corticosteroid therapy with 50 mg of prednisolone, then her condition was immediately improved together with the decrease of serum transaminase level. 10 months after, her transaminase level remains normal with 5 mg of prednisolone.