부산대학교 도서관

We evaluated the lasting stress after a surgery under a general anesthesia among 18 nondiabetic patients hospitalized in the Second Department of Oral and Maxillofacial Surgery division in Kyushu Dental Collage Hospital. The mean operation time was 61 minutes, and perioperative administration of steroid or following intravenous feeding was not carried out. All patients were administered analgesics after surgery. Serum cortisol, fasting glucose, and serum insulin levels were measured in early morning on the day (day-0), next day (day-1), and 4 days (day-4) after surgery. However, there was no significant change in these levels among these points : serum cortisol 13.4±4.2 (mean±SD), 12.0±2.7, 13.7±1.7μg/dl, fasting glucose 87±9, 83±8, 84±9mg/dl, and serum insulin level 7±5, 5±4, 5±4μU/l, on day-0, day-1, and day-4, respectively. Although small increase in serum cortisol level on day-1 was observed in 4 patients, there was no correlation to age, body-mass index of the patient, operation time, increase in the number of WBC on day-1, and positive change in serum CRP level on day-4. These results suggest that in such oral and maxillofacial surgeries as shown in this study, surgical stress rarely lasts to the next day, and fasting glucose level rarely change in non-diabetic patients.