부산대학교 도서관

A case of acute demyelinating disease mimicking a brain tumor is described. A 22-year-old woman was admitted to our hospital for evaluation of left homonymous hemianopsia. Computed tomography and magnetic resonance imaging (MRI) revealed an irregularly enhanced lesion with a marked mass effect in the right parietooccipital lobe. Subtotal excision of the mass lesion was then performed by craniotomy on the basis of a preoperative diagnosis of malignant glioma. However, histological examination of the specimen revealed the typical features of demylinating disease, including infiltration of lymphocytes in the perivascular space and demyelination. A follow-up MRI examination 2 years later revealed no evidence of recurrence of the lesion. Although demyelinating disease menifesting as an irregular mass lesion with a marked mass effect is uncommon, it is important that it be differentiated from a brain tumor.