부산대학교 도서관

Between 1986 and 1992, 10 patients (12 lesions) of advanced breast cancer were treated with multidisciplinary treatment including brachytherapy. The lesions treated included 5 primary breast tumors, 3 metastatic lesions in the contra lateral breast, 2 recurrences after external beam irradiation, 1 metastasis to the axillary lymph node and 1 metastasis to the upper arm skin. The interstitial irradiation techniques used were 192Ir low dose-rate iradiation for 5 lesions and high dose-rate for 7 lesions (including 3 with mould irradiation ). External hyperthermia as perfomed for 6 lesions and interstitial hyperthermia were perfomed for 4 lesions. The local response was CR for 3 lesions, PRa for 8 lesions, PRb for 1 lesions with the local response rate being 100%. Excellent local control could be achieved by combination external and interstitial irradiation, indicating that radiotherapy is definitely useful for the treatment of advanced breast cancer.